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CBC is a unique cannabinoid and is best known for its ability to bind to the TRPV1 and TRPA1 receptors in the brain which are responsible for pain perception. Topical applications of products high in CBC have also shown promise for the treatment of osteoarthritis symptoms and in the treatment of skin conditions such as acne.

Cannabinoids are synthesized by Cannabigerolic Acid. CBG is the decarboxylated form of this acid that appears at low levels in most cannabis plants. Because its properties are beneficial to multiple parts of the endocannabinoid system, CBG has a wide range of therapeutic uses. It is non-psychotropic and can provide analgesic and antidepressant qualities.

CBGA is often referred to as the, “Father or Mother of all Cannabinoids”. This is because CBGA is situated at the very top of the cascading reaction that creates THCA, CBDA and CBCA which, through decarboxylation, are turned into the three major cannabinoids THC, CBD and CBC. Currently there is little research being conducted on the medical benefits of CBGA, although it has shown extremely promising results when looking at the interaction between CBGA and colon cancer cells. When CBGA was applied directly to colon cancer cells not only did it destroy the cancer cells, but it also stopped the proliferation of new cancer cells. More research is certainly needed, but these preliminary results are extremely encouraging.

THCV sets itself apart from its cousin THC with its distinct lack of psychoactive effects. THCV also acts as an allosteric modulator for Delta-9-THC thus reducing its psychoactivity. It has been found to be helpful as an appetite suppressant, neuroprotectant and glycemic control in type 2 diabetics.